Cetirizine Hydrochloride
Cetirizine Hydrochloride

Cetirizine Hydrochloride: 4+ Functions, Dosage, Side Effects, and Contraindications

Cetirizine is a remedy to overcome allergy symptoms, such as colds, nasal congestion, watery eyes, sneezing, itching of the eyes, nose or throat, as well as rashes on the skin.

In the cetirizine drug, contained the active ingredient cetirizine hydrochloride (HCl) with various forms of drug preparations. Various preparations of the cetirizine drug are tablets 10 mg, syrup 5 mg, and drop.

Cetirizine works by blocking the work of histamine compounds produced by the body when exposed to allergens. This is because histamine compounds are the cause of the appearance of allergic reactions.

Cetirizine belongs to the group of anti allergic drugs (antihistamines) that do not cause drowsiness. Another anti allergic drug that is classified with cetirizine is loratadine. Unlike loratadine, although it should not cause drowsiness, some people who take cetirizine feel drowsy side effects.

Function of cetirizine hydrochloride

Cetirizine is an antihistamine drug that serves to relieve allergy symptoms such as:

  • Hives
  • Watery eyes
  • Cold
  • Itchy eyes or nose.

The drug works by blocking certain natural substances (i.e. Histamine) that the body produces during an allergic reaction.

Cetirizine can not prevent itching or treat serious allergic reactions (e.g. Anaphylactic). Therefore, if the doctor has prescribed epinephrine to treat a serious allergic reaction, do not replace it with cetirizine. Make sure you always bring an epinephrine syringe.

Cetirizine is a drug that can be obtained with or without a doctor’s prescription in pharmacies. The drug is available in the form of chewing tablets, suction tablets, and liquids.

Cetirizine Hydrochloride Dosage

The Cetirize drug should be used based on a doctor’s prescription. The reason, the dosage dose for tablets and syrups will be adjusted to the indication of allergies that occur.

Rules of use Cetirizine Tablet

Older persons: 1 tablet taken 1 time a day or 1/2 tablet, taken 2 times a day.

Cetirizine Drops rules of use

  • Children aged 6-23 months: 0.25 mL taken once a day up to 0.25 mL taken 2 times a day.
  • Children aged 2-5 years: 0.5 mL taken 1 time a day or in a divided dose in half.

Rules of use Cetirizine Syrup:

  • Children aged 2-6 years: 1/2 measuring spoonful (2.5 mL), taken 2 times a day.
  • Children aged 6-12 years: 1 measuring spoonful (5 mL), taken 2 times a day.
  • Older persons: 2 measuring spoonfuls (10 mL), taken 1 time a day.

Cetirizine hydrochloride side effects

Cetirizine has side effects after consumption, among others,


Avoid foods that are difficult to digest. Do not lie down after eating. Rest with your head higher than your feet. If you feel nauseous when you wake up in the morning, eat lean meat or cheese before going to bed.

You can also have biscuits by the bed and eat a little shortly after waking up. Drink at least six glasses of water a day.


Drink water little by little, but in frequent times. Talk to a pharmacist if you have signs of dehydration, such as urinating less frequently than usual, or dark-colored urine and a pungent smell. Do not take other medications to treat diarrhea without talking to a doctor or pharmacist.

Other side effects

  • Drowsiness,
  • Dizziness,
  • Headache,
  • Abdominal pain,
  • Weakness.
  • Difficulty sleeping
  • Tiredness
  • Laryngitis
  • Bloody cough
  • Narrowing of the airways
  • Vomiting
  • Dry mouth

Even so, not everyone will experience the same side effects.

Cetirizine Hydrochloride Contraindications

Drug Interactions

Cetirizine can cause interactions or even inhibit the performance of the drug if used in conjunction with other drugs. There are several medications that cannot be used in conjunction with Cetirizine, including ritonavir, midodrine, and medications that have side effects of drowsiness, dry mouth, and difficulty urinating.

It is recommended to consult the use of the Cetirizine drug in conjunction with other drugs or supplements to a doctor or pharmacist. This is to prevent the risk of drug interactions.

Risk Groups

Although rare, it is recommended to consult your doctor if you have certain health conditions such as being pregnant, breastfeeding, or having health problems such as impaired liver function, kidney disease, and heart disease.

Last Updated on January 16, 2022 Reviewed by Market Health Beauty Team