Remdesivir Uses and Side Effects – Remdesivir is an antiviral drug that is being researched and considered to have the potential to cope with a Corona or COVID-19 viral infections. Remdesivir is a broad spectrum antivirus and has been studied to address the Ebola, MERS, and SARS.
Until now there has been no really effective drug to cope with Coronavirus infection or COVID 19. A number of drugs, including remdesivir are being researched further to ensure its effectiveness and safety in addressing this viral infection.
Remdesivir Uses and Side Effects
Here are The Remdesivir Uses and Side Effects:
Remdesivir Uses
Remdesivir, or GS-5734, is a new antiviral drug that belongs to the class of analog nucleotides. This antivirus-type analog nucleotide drug essentially works by interfering with the virus’s genetic material. That way, genetic replication of the virus can be inhibited.
The drug was developed by Gilead Sciences, a biopharmaceutical company based in the United States. The drug was originally used as a treatment option for Ebola disease, an outbreak that had spread in Africa some time ago.
Based on a study in the journal Nature, Remdesivir has an antiviral effect on various variants of the Ebola virus as well as several other types of RNA viruses, such as phylog viruses and arenaviruses.
Remdesivir also provided as a remedy for the fight against the disease due to coronavirus infection, namely SARS and MERS disease. A study found in Science Translational Medicine suggests that the drug can inhibit the development of SARS-CoV and MERS-CoV viruses in the body.
Currently, Remdesivir is included in several medications that are currently in Test stage as a COVID-19 treatment, which became a global pandemic in March 2020. The COVID-19 disease itself is caused by the latest type of Coronavirus, namely SARS-COV-2 or SARS type 2.
A research contained in the journal Cell Research describes how remdesivir drugs combined with chloroquine malaria medication can control viral infections of the cause of COVID-19.
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Warning before using Remdesivir
- Do not use Remdesivir if you have allergies to ingredients or content in this drug.
- Do not use Remdesivir when you suffer from kidney disease or liver disease.
- Do not use this drug if you are undergoing dialysis..
- Do not use Remdesivir if it is pregnant or breastfeeding.
- Immediately to the doctor if you experience drug allergic reactions or overdose after taking this drug.
How to use remdesivir drugs?
Remdesivir is a medication that should only be used according to a doctor’s prescription. Follow the medication rules provided by your doctor or pharmacist before starting treatment. Always read the medication instructions before using this medication.
This drug is an intravenous injection drug, meaning it must be injected through the veins. Do not use this drug exceeding the recommended dose, less, or longer than suggested.
If you have further questions regarding the rules of using Remdesivir, consult with your doctor or pharmacist.
Remdesivir Drug Interactions
Based on the research that is still being developed, this compound may have no effect on the effectiveness of other drugs that you take at the same time. Conversely, other medications you use concurrently may trigger interactions against these antiviral compounds.
Other drugs such as antibiotics Clarithromycin and Rifampicin may increase the levels of this antiviral compound in the bloodstream or may decrease it.
Side effects of Remdesivir
Common antiviral drug side effects, including:
- Nausea
- Vomiting
In trials conducted during the Ebola outbreak in 2014, this compound triggered side effects such as elevated levels of liver enzymes that may or may not indicate liver damage. While in the COVID-19 drug research, a similar increase in liver enzymes occurs in three patients in the United States.
A study of Gilead Sciences published in the New England Journal of Medicine reported preliminary results from the use of remdesivir. Expressed, more than half of COVID 19 patients in this study experienced side effects from medications, such as rash and diarrhea to acute renal injury.
The study evaluated the response of 53 patients who were given the remdesivir drug based on voluntary use. All patients are from different hospitals, which are 22 hospitals in the U.S., 22 in Europe and Canada, and 9 in Japan.
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