ARB Medications For High Blood Pressure, and Warnings – ARB or angiotensin II receptor blockers are a type of drugs used to treat high blood pressure and heart failure. In fact, ARB has almost the same effect as ACE inhibitors, which are also one of the drug groups to deal with high blood pressure. It’s just that the workings of these two drug groups are different.
ARB works by inhibiting the effects of angiotensin II or compounds that narrow blood vessels. By inhibiting angiotensin II, blood vessels can be widened to allow blood circulation to run smoothly while lowering blood pressure.
ARB medications are usually recommended by doctors to patients who are unable to respond to ACE inhibitors as well. In addition to hypertension, the ARB can also be used to treat heart failure, as well as prevents kidney failure in diabetics or hypertension.
Each variant of the angiotensin receptor blocker (ARB) drug is important in the implementation of hypertension, based on the latest scientific findings. It is important to tailor therapy for each individual patient, especially in patients with high blood pressure who are at risk of targeted organ damage.
A comprehensive review of studies on ARB as of August 2015 investigates ARB efficacy in a variety of clinical conditions beyond hypertension.
With the primary goal of preventing cardiovascular events, telmisartan and losartan are ARB options in patients with high cardiovascular risk and have a general need to lower cardiovascular risk. In the case of heart failure: losartan, candesartan, or Valsartan should be selected.
Valsartan can also be considered for patients with left ventricular dysfunction following a recent myocardial infarction.
In hypertensive patients with a higher risk of stroke, losartan should be the primary therapeutic option; telmisartan, eprosartan and candesartan also showed a decreased risk in this subpopulation.
While patients with atrial fibrillation / AF, the use of telmisartan is recommended; losartan, candesartan, and Valsartan showed a decrease in onset AF incidence; then the use of ARB drugs is also beneficial for patients with AF risk.
ARB Medications For High Blood Pressure
Hypertension is a medical condition characterized by chronic increases in blood pressure. Hypertension is one of the most frequent causes of death in the world. Nearly a billion people worldwide are at risk of heart failure, heart attack, stroke, kidney failure and blindness due to hypertension.
Hypertension occurs when blood volume increases and/or the blood vessels narrow, making the heart pump harder to supply oxygen and nutrients to every cell in the body.
Blood pressure is measured based on the pressure on the walls of blood vessels (whose magnitude is expressed in mmHg). If blood pressure exceeds normal levels, then the risk of damage can occur to vital organs in the body, such as the heart, kidneys, brain, and eyes. This increases the risk of potentially fatal events such as heart attacks and strokes.
Hypertension can be caused by a variety of factors and often varies by individual. Treatment of hypertension itself is more aimed at lowering morbidity and mortality of patients. With the treatment or control of blood pressure, various complications that can be triggered by hypertension can be prevented. One of the kinds of drugs used to overcome and control hypertension is angiotensin receptor blockers (ARB).
Angiotensin receptor blocker (ARB) is an antihypertensive drug that works by lowering blood pressure through the renin-angiotensin-aldosterone system. ARB is able to inhibit angiotensin II bonded with its receptors, so it will directly cause vasodilation, decrease vasopressin production, and reduce aldosterone secretion. These three effects together will cause a decrease in blood pressure.
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Warning:
- Pregnant women, nursing mothers, or women planning a pregnancy should not take this drug if it is not recommended by a doctor.
- Please be careful in taking this drug if you have a history of swelling beneath the surface of the skin (angioedema), severe kidney or liver disease, heart failure, risk of low blood pressure (hypotension), the risk of hyperkalemia, narrowing of arterial blood vessels, heart valve disease, bile duct disease, and lack of sodium levels.
- Notify your doctor if you are using other medications, including, supplements and herbal products.
- In the case of an allergic reaction or overdose, see a doctor immediately.
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