Chlorthalidone 25 mg: Usage, How It Works, Dosage, and Side Effects -Chlortalidone is a drug which is categorized in groups of thiazide diuretics drugs. Thiazide diuretics serves to reduce the water content in your body by way of increasing the amount of water in Your urine. Chlortalidone is a drug, also known as the ‘ water ‘ tablets.
Usage / Indications:
Chlortalidone is a drug that is used to:
- Treat high blood pressure (hypertension).
- Treating heart failure.
- Reduce shelter liquid that causes disease of kidney and liver.
- Treat diabetes insipidus (a condition in which a person’s urine volume too much and often thirst).
- To treat fluid retention (edema) in people with congestive heart failure (CHF), cirrhosis of the liver, kidney disorders, or edema, caused by the use of steroids and estrogen.
How it works.
The workings of the Chlortalidone drug is to prevent the re-absorption of chlorides and sodium by blocking the Na + / Cl symporter in the distal tubule (the nephron in the kidney, the nephron is the smallest unit of kidney function).
Symporter is an integral membrane protein that is involved in the transport process several types of molecules along the cell membrane.
Chlorthalodine drugs indirectly increase the excretion through the mechanism of the exchange of sodium-potassium, this may happen because Chlortalidone increases sodium transfer to the distal renal tubule.
Of the process, the concentration of potassium and chloride in the blood become lower, as well as the metabolic alkalosis (metabolic conditions, where the level of acidity of the network is increased above the normal limits).
However, the efficacy of this Chlortalidone drug is not affected by the acid alkaline balance of the users of the drug.
Diuretic drugs lower blood pressure by decreasing precipitation of the heart as well as bring down the volume of extracellular fluid (outside the cell) and plasma.
How Chlorthalidone 25 mg Works Video
Read also: Olanzapine side effects.
- 25-100 mg through the mouth (per oral), 2 times a day.
- Maximum dose: 200 mg/day
How do You use Chlortalidone 25 mg?
Chlortalidone 25 mg is a drug that is best used in the morning with food. Swallow the tablet with drinking a glass of water. You should avoid foods with lower levels of salt because chlortalidone can reduce the amount of salt in your body.. If you’re in the diet with foods that contain a bit of salt, tell your doctor before using Chlortalidone.
Endocrine and metabolic effects (hyperuricemia and can cause gout in some patients, hypochloremic alkalosis, hypokalemia, hypomagnesemia, hyperglycemia & glycosuria in people with diabetes mellitus or other vulnerable patients); GI effects (GI, N / V irritation, constipation, anorexia, diarrhea); Other effects (photosensitivity reactions, postural hypotension, impotence, hypersensitivity reactions).
Generic Chlorthalidone Side Effects:
- Levels of potassium, sodium, and magnesium are low in the body.
- High calcium levels and uric acid in the body.
- High blood sugar levels in those with diabetes.
- CNS effects (headache, dizziness, head feels light).
- Abdominal pain.
Serious Chlorthalidone Side Effects:
Contact your doctor immediately if you experience any of the following serious side effects:
- Sore throat with fever.
- Unusual bruising or bleeding.
- Severe skin rash with flaking skin.
- Difficulty swallowing or breathing.
Chlorthalidone 25 mg Warning.
Chlorthalidone control, but does not cure the condition. You have to keep taking this medication even if you feel healthy. You should not stop taking any medication without consulting with your doctor first.
You should tell your doctor if you have ever suffered from diabetes, kidney disease, or/ parathyroid before taking chlorthalidone. In addition, make sure your doctor knows that you are taking this medication before any kind of surgery, including dental surgery.
Chlorthalidone may make you drowsy, so you should not drive or operate machinery until you know how it will affect you. You may experience urination when you first start taking chlorthalidone, but these symptoms should disappear after a few weeks.
Read also: Oxybutynin side effects.
Thank you very much for reading Chlorthalidone 25 mg: Usage, How It Works, Dosage, and Side Effects, hopefully useful.